HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tyramine → HCID 58603756, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tyramine | HCID 5610 | — |
| Reactant | [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-ethyl-pyridin-3-ylmethyl-amine | HCID 86603260 | — |
| Product | HCID 58603756 | HCID 58603756 | — |
Reaction Steps
Intermediate 23 was coupled with tyramine following procedure F. LC-MS showed the product had the expected M+H+ of 440. 1H NMR (Varian 300 MHz, CDCl3, shifts relative to the solvent peak at 7.24 ppm) δ 8.63 (s, 1H) 8.49 (m, 1H) 8.26 (m, 1H) 8.15 (s, 1H) 8.05 (s, 1H) 7.45 (m, 2H) 7.25 (m, 1H) 7.05 (m, 3H) 6.99 (d, 1H) 6.75 (m, 4H) 3.4-3.8 (m, 4H) 2.88 (t, 2H) 2.75 (t, 2H) 2.55 (m, 2H) 1.05 (t, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268822B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-3e82b2126400458d95071f1989c94f43 |
| Source note | uspto-grants-2012_09 |