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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386403Generated: October 25, 2026

O-Methyltyramine → 1-(3-{2-[2-(4-Methoxy-phenyl)-ethylamino]-pyrimidin-4-yl}-phenyl)-ethanone

https://huagongshe.com/reaction/2386403

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-MethyltyramineHCID 4657—
Reactant1-[3-(2-Chloro-pyrimidin-4-yl)-phenyl]-ethanoneHCID 24901839—
Product1-(3-{2-[2-(4-Methoxy-phenyl)-ethylamino]-pyrimidin-4-yl}-phenyl)-ethanoneHCID 67045540—

Reaction Steps

Intermediate 38 was coupled with 2-(4-Methoxy-phenyl)-ethylamine following procedure F. LC-MS showed the product had the expected M+H+ of 348.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-d5ddaf116a304e2bbf28d4dbf4b217ab
Source noteuspto-grants-2012_09