Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl chloride → (3-Benzoylamino-propyl)-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | tert-Butyl (3-aminopropyl)carbamate | HCID 2735700 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | (3-Benzoylamino-propyl)-carbamic acid tert-butyl ester | HCID 10492863 | — |
반응 단계
(3-Amino-propyl)-carbamic acid tert-butyl ester (1.6 g) was treated with benzoyl chloride (1.1 eq.) and triethylamine (1.5 eq) in methylene chloride (50 mL). The reaction mixture was washed with 1 N HCl, sat, NaHCO3, and sat NaCl and the solvent removed to give product. LC-MS showed the product had the expected M+H+ of 279.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08268822B2 |
| 출처 데이터셋 | uspto-grants-2012_09 |
| ORD ID | ord-dd27532696644c2181c9445e2b220bfc |
| 출처 메모 | uspto-grants-2012_09 |