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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386407Generated: October 26, 2026

2,4-Dichloropyrimidine → 2-Chloro-4-(3-isopropoxy-phenyl)-pyrimidine

https://huagongshe.com/reaction/2386407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichloropyrimidineHCID 77531—
Reactant3-Isopropoxybenzeneboronic acidHCID 5083932—
Product2-Chloro-4-(3-isopropoxy-phenyl)-pyrimidineHCID 24901819—

Reaction Steps

2,4 dichlorpyrimidine was coupled with 3-isopropoxyphenylboronic acid following procedure A. LC-MS showed the product had the expected M+H+ of 249.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-490302d569a84b308c4fb81181af23cd
Source noteuspto-grants-2012_09