HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxytyramine → HCID 58603758, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxytyramine | HCID 1669 | — |
| Reactant | 2-Chloro-4-(4-propoxy-phenyl)-pyrimidine | HCID 79079142 | — |
| Product | HCID 58603758 | HCID 58603758 | — |
Reaction Steps
Intermediate 50 was coupled with 4-(2-Amino-ethyl)-2-methoxy-phenol following procedure F. LC-MS showed the product had the expected M+H+ of 380. 1H NMR (Varian 300 MHz, DMSO-d6, shifts relative to the solvent peak at 2.49 ppm) δ 8.0 (d, 1H), 7.1-7.0 (m, 4H) 6.8 (s, 1H), δ 6.7-6.6 (m, 3H), δ 4.0 (t, 2H), δ 3.7 (s, 3H), 3.5 (t, 2H), δ 2.7 (t, 2H), δ 1.8-1.7 (m, 2H), 0.9 (t, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268822B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-f533c9c95ba94f388ccac9f74810eba9 |
| Source note | uspto-grants-2012_09 |