HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetylphenylboronic acid → 1-(3-{2-[2-(4-Hydroxy-phenyl)-ethylamino]-pyrimidin-4-yl}-phenyl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetylphenylboronic acid | HCID 2734310 | — |
| Reactant | 4-[2-(4-Chloro-pyrimidin-2-ylamino)-ethyl]-phenol | HCID 86603281 | — |
| Product | 1-(3-{2-[2-(4-Hydroxy-phenyl)-ethylamino]-pyrimidin-4-yl}-phenyl)-ethanone | HCID 67044689 | — |
Reaction Steps
Intermediate 61 was coupled with 3-acetyl phenylboronic acid following procedure A. LC-MS showed the product had the expected M+H+ of 334.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268822B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-97c6f457b1524b6f8e19be16d467de8c |
| Source note | uspto-grants-2012_09 |