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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386441Generated: October 25, 2026

Isopropylamine → [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-isopropyl-amine

https://huagongshe.com/reaction/2386441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
Reactant{3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-propyl}-carbamic acid tert-butyl esterHCID 86603243—
Product[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-isopropyl-amineHCID 86603283—

Reaction Steps

Intermediate 2 was coupled with isopropylamine following procedure B. LC-MS showed the product had the expected M+H+ of 262.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-41d9765b78d44e43ada9bf1efa2a43c3
Source noteuspto-grants-2012_09