HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-isopropyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | {3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-propyl}-carbamic acid tert-butyl ester | HCID 86603243 | — |
| Product | [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-isopropyl-amine | HCID 86603283 | — |
Reaction Steps
Intermediate 2 was coupled with isopropylamine following procedure B. LC-MS showed the product had the expected M+H+ of 262.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268822B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-41d9765b78d44e43ada9bf1efa2a43c3 |
| Source note | uspto-grants-2012_09 |