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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386467Generated: October 25, 2026

2,4-Dichloropyrimidine → 5-(2-Chloro-pyrimidin-4-yl)-2-methoxy-benzaldehyde

https://huagongshe.com/reaction/2386467

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichloropyrimidineHCID 77531—
Reactant(3-Formyl-4-methoxyphenyl)boronic acidHCID 2759225—
Product5-(2-Chloro-pyrimidin-4-yl)-2-methoxy-benzaldehydeHCID 53363596—

Reaction Steps

2,4 dichloropyrimidine and 3-formyl 4-methoxy phenyl boronic acid were coupled following procedure A. LC-MS showed the product was >95% pure and had the expected M+H+ of 249.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-66b9f6a1d247488aa86d830e557af6a9
Source noteuspto-grants-2012_09