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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386470Generated: October 26, 2026

2,4-Dichloropyrimidine → 5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehyde

https://huagongshe.com/reaction/2386470

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichloropyrimidineHCID 77531—
Reactant(4-Fluoro-3-formylphenyl)boronic acidHCID 2778651—
Product5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehydeHCID 24901981—

Reaction Steps

2,4 dichloropyrimidine and 3-formyl 4-fluorophenyl boronic acid were coupled following procedure A. LC-MS showed the product was >95% pure and had the expected M+H+ of 237.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-5e9a4535f4724e70857854daaf2e163c
Source noteuspto-grants-2012_09