HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-aminoazetidine-1-carboxylate → 3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-azetidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-aminoazetidine-1-carboxylate | HCID 1516507 | — |
| Reactant | 3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde | HCID 24901965 | — |
| Product | 3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-azetidine-1-carboxylic acid tert-butyl ester | HCID 86603298 | — |
Reaction Steps
Intermediate 1 was coupled with 3-Amino-azetidine-1-carboxylic acid tert-butyl ester following procedure B. LC-MS showed the product had the expected M+H+ of 375.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268822B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-0d1d08444b254e5a840ff0892044becc |
| Source note | uspto-grants-2012_09 |