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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386546Generated: November 1, 2026

3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde → HCID 86603322, compound

https://huagongshe.com/reaction/2386546

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Chloro-pyrimidin-4-yl)-benzaldehydeHCID 24901965—
Reactanttert-Butyl 3-cyanopiperazine-1-carboxylateHCID 53487922—
ProductHCID 86603322HCID 86603322—

Reaction Steps

Intermediate 1 was coupled with 3-cyano-piperazine-1-carboxylic acid tert-butyl ester (generated according to literature procedure (ref 3)) following procedure B. LC-MS showed the product had the expected M+H+ of 414.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-9a0e415f4def4db99f3c8a816800f96b
Source noteuspto-grants-2012_09