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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386548Generated: October 31, 2026

3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde → HCID 86603323, compound

https://huagongshe.com/reaction/2386548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Chloro-pyrimidin-4-yl)-benzaldehydeHCID 24901965—
Reactant2-Cyano-piperazine-1-carboxylic acid benzyl esterHCID 67045119—
ProductHCID 86603323HCID 86603323—

Reaction Steps

Intermediate 1 was coupled with 2-cyano-piperazine-1-carboxylic acid benzyl ester (generated according to literature procedure (ref 4)) following procedure B. LC-MS showed the product had the expected M+H+ of 448.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-e2fa51aca4e54fe0909615316806aba5
Source noteuspto-grants-2012_09