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HRID2386836

反应详情

EQUATION

反应方程式

HRID 2386836 的结构方程式

REACTANTS

反应物

2
结构：CC(C)Oc1cc(C(F)(F)F)c2cc(Br)ccc2n1
HCID22279301

6-Bromo-2-(1-methylethoxy)-4-(trifluoromethyl)quinoline

C13H11BrF3NO

结构：CCOC(C)=O.O
HCID22728543

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)Oc1cc(C(F)(F)F)c2cc(C(=O)O)ccc2n1
HCID66697096

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized by carbonylation of 6-bromo-2-isopropoxy-4-trifluoromethyl-quinoline (CAS [328955-63-1]) in ethyl acetate/water using 50 bar CO, PdCl2 dppf CH2Cl2, 80° C. for 20 h. Light grey solid. MS (m/e, ISP neg. ion)=298.3 [M−H+].