HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-chloropyrimidine-5-carboxylate → HCID 66697039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-chloropyrimidine-5-carboxylate | HCID 12627752 | — |
| Reactant | 5-[2-(2-Chloro-4-hydroxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-3-methyl-3H-benzooxazol-2-one | HCID 66696986 | — |
| Product | HCID 66697039 | HCID 66697039 | — |
Reaction Steps
The title compound was prepared in analogy to Example 196 from 5-[2-(2-chloro-4-hydroxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-3-methyl-3H-benzooxazol-2-one (obtained in Example 172) by alkylation with methyl-2-chloropyrimidine-5-carboxylate [CAS Reg. No. 287714-35-6]. MS (m/e)=538.2 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268820B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-5e7015a517cf4c68b3268544882326a0 |
| Source note | uspto-grants-2012_09 |