Anthranilic Acid → HCID 11675524, compound

HRID 2386930Notes

Reaction equation

HRID 2386930 reaction equation
[C:1]([OH:10])(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[N:11]1([CH2:17][CH2:18][CH2:19][O:20][C:21]2[CH:27]=[CH:26][C:24]([NH2:25])=[CH:23][CH:22]=2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1.N1(CCCOC2C=CC(N)=CC=2)CC[CH2:30][CH2:29]1.N[C:45]1C=NC(OCCCN2CCCCC2)=NC=1>>[CH3:29][C:30]1[N:25]([C:24]2[CH:23]=[CH:22][C:21]([O:20][CH2:19][CH2:18][CH2:17][N:11]3[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]3)=[CH:27][CH:26]=2)[C:1](=[O:10])[C:2]2[C:3](=[CH:5][CH:6]=[CH:7][C:8]=2[CH3:45])[N:4]=1

Participants

5

Reactant 4

HCID 227Anthranilic AcidHCID 129353854-[3-(Pyrrolidin-1-yl)propoxy]anilineHCID 219749324-[3-(1-Piperidinyl)propoxy]anilineHCID 23151298HCID 23151298, compound

Product 1

HCID 11675524HCID 11675524, compound

Procedure

The compound of Example 19-62 can be manufactured by same method as that of Example 18, a method based thereon or a combination of these with a conventional method, using the corresponding anthranilic acid, acid anhydride and 4-[3-(1-piperidinyl)propoxy]aniline, 4-[3-(1-pyrrolidinyl)propoxy]aniline or 5-amino-2-[3-(1-piperidinyl)propoxy]pyrimidine as starting materials.

Sources & evidence

ORD record
ord-05a5f7e98914403c9e35f088353da610
Source dataset
uspto-grants-2012_09
Patent number
US08268842B2

Reaction notes

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