1-Benzyl-3-pyrrolidinone → N-benzyl-3-pyrrolidinol

HRID 2386947Notes

Reaction equation

HRID 2386947 reaction equation
[CH2:1]([N:8]1[CH2:12][CH2:11][C:10](=[O:13])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BH4-].[Na+]>>[CH2:1]([N:8]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 698901-Benzyl-3-pyrrolidinoneHCID 4311764Sodium borohydride

Product 1

HCID 69889N-benzyl-3-pyrrolidinol

Procedure

1-benzyl-3-pyrrolidinone was reduced with sodium borohydride according to Example 117-(1), and the target compound was obtained.

Workup

  1. customthe target compound was obtained

Sources & evidence

ORD record
ord-d4f9d595a6434518af4f276f80d313b8
Source dataset
uspto-grants-2012_09
Patent number
US08268842B2

Reaction notes

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