HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 2-Amino-6-bromobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 2-Bromo-6-nitrotoluene | HCID 123537 | — |
| Reactant | 2-Bromo-6-nitrobenzoic acid | HCID 13531381 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Amino-6-bromobenzoic acid | HCID 10560649 | — |
Reaction Steps
The target compound was obtained by reducing 2-bromo-6-nitrobenzoic acid with iron in a mixed solvent of methanol and ammonium chloride aqueous solution. 2-bromo-6-nitrobenzoic acid was manufactured by the method described in the literature (J. Chem. Soc. Perkin Trans. 1, 1991, p. 1565) using 2-bromo-6-nitrotoluene as starting material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268842B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-d2add1f51d3e4757ac0a0407052c26af |
| Source note | uspto-grants-2012_09 |