p-Fluoronitrobenzene → HCID 23151356, compound

HRID 2386975Notes

Reaction equation

HRID 2386975 reaction equation
[N:1]1([CH:6]([CH3:10])[CH2:7][CH2:8][OH:9])[CH2:5][CH2:4][CH2:3][CH2:2]1.[N+:11]([C:14]1[CH:19]=[CH:18][C:17](F)=[CH:16][CH:15]=1)([O-])=O>>[N:1]1([CH:6]([CH3:10])[CH2:7][CH2:8][O:9][C:17]2[CH:18]=[CH:19][C:14]([NH2:11])=[CH:15][CH:16]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 9590p-FluoronitrobenzeneHCID 100120193-(Pyrrolidin-1-yl)butan-1-ol

Product 1

HCID 23151356HCID 23151356, compound

Procedure

The target compound was obtained by the method according to Example 18, using 3-pyrrolidin-1-yl-butan -1-ol (racemic mixture) manufactured by the method described in the literature (J. Org. Chem., 1949, Vol. 14, p. 862) and 4-nitrofluorobenzene as starting materials.

Workup

  1. customThe target compound was obtained by the method

Sources & evidence

ORD record
ord-8e4e44cd89b64c8a9359a241434c1d9a
Source dataset
uspto-grants-2012_09
Patent number
US08268842B2

Reaction notes

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