2-Amino-4-chloropyrimidine → HCID 44609410, compound

Participants

Reaction Steps

The product of Example 3B (45 mg, 0.126 mmol) and 2-amino-6-chloropyrimidine (21 mg, 0.164 mmol) were treated under the conditions described in Example 1F to afford the title compound. 1H NMR (300 MHz, CDCl3) δ ppm 7.86 (d, J=5.16 Hz, 1H) 7.64-7.70 (m, 1H) 7.28-7.40 (m, 2H) 7.17-7.23 (m, 1H) 5.77 (d, J=5.95 Hz, 1H) 5.30 (s, 1H) 5.02 (t, J=5.55 Hz, 1H) 4.63 (s, 2H) 3.59 (q, J=6.35 Hz, 2H) 3.32 (d, J=5.16 Hz, 2H) 2.58 (t, J=6.54 Hz, 2H) 2.05-2.24 (m, 4H) 1.83-1.96 (m, 2H); MS (ESI+) m/z 377.0 (M+H)+.

Provenance & Evidence