化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → 1-Methyl-2-nitro-4-propoxybenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 3-Nitro-p-cresol | HCID 16271 | — |
| 反応物 | 1-Iodopropane | HCID 33643 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 1-Methyl-2-nitro-4-propoxybenzene | HCID 58764279 | — |
反応手順
Potassium carbonate (13.5 g, 0.098 mol) followed by 1-iodopropane (9.56 mL, 0.098 mol) were added to a solution of 4-methyl-3-nitro-phenol (15 g, 0.098 mol) in DMF (100 mL). The mixture was stirred for 5 hours and then partitioned between H2O and EtOAc. The organic layer was washed with satd NaHCO3, brine, dried over Na2SO4 and concentrated to a clear oil (17.5 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08268835B2 |
| 出典データセット | uspto-grants-2012_09 |
| ORD ID | ord-4cb59786c59d40de9611c46f70ef2fe4 |
| 出典メモ | uspto-grants-2012_09 |