Thionyl Chloride → HCID 58764270, compound

HRID 2387072Notes

Reaction equation

HRID 2387072 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[C:4]([CH2:11][CH3:12])[CH:3]=1.O=S(Cl)[Cl:15]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:15])=[O:7])=[C:4]([CH2:11][CH3:12])[CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 106570054-Bromo-2-ethylbenzoic acid

Product 1

HCID 58764270HCID 58764270, compoundYield 96%

Procedure

A solution of 4-bromo-2-ethyl-benzoic acid (1.72 g, 7.51 mmol) in SOCl2 (50 mL) was heated to 90° C. and stirred for 2 hours. The volatiles were removed in vacuo to yield a brown solid (1.80 g, 96%). 1H NMR (300 MHz, CDCl3): δ 1.22 (t, J=7.4 Hz, 3 H), 2.89 (q, J=7.5 Hz, 2 H), 7.49 (m, 2 H), 8.03 (d, J=9.0 Hz, 1 H).

Workup

  1. customThe volatiles were removed in vacuo

Sources & evidence

ORD record
ord-fed7a8bdf6e944bd9bd0d329aeeb52c9
Source dataset
uspto-grants-2012_09
Patent number
US08268835B2

Reaction notes

Loading…