HCID 59372566, compound → HCID 67428865, compound

Participants

Reaction Steps

N-(3-nitrobenzyl)-N′-ethylsulfamide was dissolved in methanol (100 mL) and to the solution was added 10% Pd—C. The reaction mixture was reacted under hydrogen atmosphere (˜40 psi) for 1 h. The catalyst was filtered off over celite and washed with methanol. The filtrate was evaporated to give N-(3-aminobenzyl)-N′-ethylsulfamide. 1H NMR (DMSO-d6): δ 1.03 (t, J=7.2 Hz, 3H), 2.83 (p, J=6.9 Hz, 2H), 3.81 (d, J=6.3 Hz, 2H), 5.02 (s, 2H), 6.41 (t, J=7.8 Hz, 2H), 6.51 (s, 1H), 6.76 (t, J=5.7 Hz, 1H), 6.91 (t, J=7.5 Hz, 1H), 7.16 (t, J=6.3 Hz, 1H).

Provenance & Evidence