Dimethylformamide dimethyl acetal → HCID 67132196, compound

Participants

Reaction Steps

To a round bottom flask was added 2-[3-(tert-butyldimethylsilanyloxy)-4,4,4-trifluoro-1,1-dimethylbutyl]benzenesulfonamide (750 mg, 1.76 mmol) in 25 mL of dry dichloromethane, followed by the addition of N,N-dimethylformamide dimethyl acetal (420 mg, 3.53 mmol). The reaction mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated under high vacuum to afford 820 mg (100%) of 2-[3-(tert-butyldimethylsilanyloxy)-4,4,4-trifluoro-1,1-dimethylbutyl]-N-[1-dimethylaminomethylidene]benzenesulfonamide. MS (ES+) m/z 481 [M+H]+.

Provenance & Evidence