p-Toluenesulfonic acid → HCID 13613731, compound

Participants

Reaction Steps

To a stirred solution of 1,2,6-hexanetriol (10.0 g, 74.6 mmol) in acetone (50 ml) was added dichloromethane (50 ml), p-toluene sulphonic acid (1 mol %, catalyst) and anhydrous magnesium sulphate (50 g). The mixture was allowed to stir at ambient temperature for 24 hours. The MgSO4 was then removed via filtration and the acetone/dichloromethane solution washed with saturated sodium bicarbonate solution (1×30 ml) and water (2×30 ml). The organic solution was then dried over anhydrous MgSO4, filtered and solvent removed in vacuo, to yield the product as a colourless liquid. Yield=13.0 g (79%).

Provenance & Evidence