HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (S)-3-(Benzyl((S)-1-phenylethyl)amino)heptanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | (S)-tert-Butyl 3-(benzyl((S)-1-phenylethyl)amino)heptanoate | HCID 68104424 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (S)-3-(Benzyl((S)-1-phenylethyl)amino)heptanoic acid | HCID 68414644 | 165.1% |
Reaction Steps
The product from step (ii) (12 g) was dissolved in DCM (40 mL) and TFA (2 mL) and the reaction mixture stirred for 24 h. The solvents were evaporated to give the subtitle compound 17 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268990B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-fd8c30d190f34c6b9d0683c009fca8f1 |
| Source note | uspto-grants-2012_09 |