反应详情

A mixture of the product from step (ii) (23.35 g) and guanidine carbonate (15.9 g) in EtOH (300 ml) was heated under reflux for 24 h. The mixture was cooled and the solid filtered and washed with EtOH, water, EtOH then diethyl ether and dried to afford the subtitle compound, 11.36 g.

1. temperaturewas heated
2. temperatureunder reflux for 24 h
3. temperatureThe mixture was cooled
4. filtrationthe solid filtered
5. washwashed with EtOH, water, EtOH
6. dry with materialdiethyl ether and dried