HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 86633411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | (2S)-1-Amino-2-butanol | HCID 6995554 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86633411 | HCID 86633411 | — |
Reaction Steps
To the product from step (ii) (310 mg) in DMF (10 mL), tert-butylchlorodimethylsilane (734 mg) was added followed by imidazole (474 mg) and stirred at rt for 24 h. The mixture was washed with water and extracted with EtOAc, dried and the solvent removed to give the subtitle compound as a yellow oil, 610 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268990B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-b3232efce3c34bd9b858e2e9481ecf73 |
| Source note | uspto-grants-2012_09 |