HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Hydroxyquinoline → 6-(3-Chloro-5-nitropyridin-2-yloxy)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Hydroxyquinoline | HCID 11374 | — |
| Reactant | 2,3-Dichloro-5-nitropyridine | HCID 2763106 | — |
| Product | 6-(3-Chloro-5-nitropyridin-2-yloxy)quinoline | HCID 68802604 | — |
Reaction Steps
Quinolin-6-ol was reacted with 2,3-dichloro-5-nitro pyridine to obtain 6-(3-chloro-5-nitropyridin-2-yloxy)quinoline which was further converted to 5-chloro-6-(quinolin-6-yloxy)pyridin-3-amine as per the procedure described in preparation 1 step iii and iv.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08269010B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-c593050396b94ce3b02d8a44de2555ec |
| Source note | uspto-grants-2012_09 |