3,5-Dimethylbenzenesulfonyl chloride → N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)-3,5-dimethylbenzenesulfonamide

HRID 2388048Notes

Reaction equation

HRID 2388048 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[N:10]=[CH:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2.[CH3:20][C:21]1[CH:22]=[C:23]([S:28](Cl)(=[O:30])=[O:29])[CH:24]=[C:25]([CH3:27])[CH:26]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:19][S:28]([C:23]2[CH:24]=[C:25]([CH3:27])[CH:26]=[C:21]([CH3:20])[CH:22]=2)(=[O:30])=[O:29])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[N:10]=[CH:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2

Participants

3

Reactant 2

HCID 27362353,5-Dimethylbenzenesulfonyl chlorideHCID 687937575-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine

Product 1

HCID 68803662N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)-3,5-dimethylbenzenesulfonamide

Procedure

The title compound was prepared by reacting 5-chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 2) and 3,5-dimethylbenzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-c976946d1cb243838377aa07194eec44
Source dataset
uspto-grants-2012_09
Patent number
US08269010B2

Reaction notes

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