3-Methylbenzenesulphonyl chloride → N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)-3-methylbenzenesulfonamide

HRID 2388051노트

반응식

HRID 2388051 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[N:10]=[CH:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2.[CH3:20][C:21]1[CH:22]=[C:23]([S:27](Cl)(=[O:29])=[O:28])[CH:24]=[CH:25][CH:26]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:19][S:27]([C:23]2[CH:24]=[CH:25][CH:26]=[C:21]([CH3:20])[CH:22]=2)(=[O:29])=[O:28])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[N:10]=[CH:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2

참가 물질

3

반응물 2

HCID 27345953-Methylbenzenesulphonyl chlorideHCID 687937575-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine

생성물 1

HCID 24852252N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)-3-methylbenzenesulfonamide

실험 절차

The title compound was prepared by reacting 5-chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 2) and 3-methylbenzene-1-sulfonyl chloride.

출처 및 근거

ORD 기록
ord-747a39e941bb4e0e92cd219fe9c1a90a
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08269010B2

반응 노트

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