2-Chloro-4-fluorobenzene-1-sulfonyl chloride → HCID 24852361, compound

HRID 2388057Notes

Reaction equation

HRID 2388057 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[N:10]=[CH:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2.[Cl:20][C:21]1[CH:26]=[C:25]([F:27])[CH:24]=[CH:23][C:22]=1[S:28](Cl)(=[O:30])=[O:29]>>[Cl:20][C:21]1[CH:26]=[C:25]([F:27])[CH:24]=[CH:23][C:22]=1[S:28]([NH:19][C:4]1[CH:5]=[N:6][C:7]([O:8][C:9]2[N:10]=[CH:11][C:12]3[C:17]([CH:18]=2)=[CH:16][CH:15]=[CH:14][CH:13]=3)=[C:2]([Cl:1])[CH:3]=1)(=[O:30])=[O:29]

Participants

3

Reactant 2

HCID 5228462-Chloro-4-fluorobenzene-1-sulfonyl chlorideHCID 687937575-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine

Product 1

HCID 24852361HCID 24852361, compound

Procedure

The title compound was prepared by reacting 5-chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 2) and 2-chloro-4-fluorobenzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-3f79f51eda374d809ed1526886dcfe2b
Source dataset
uspto-grants-2012_09
Patent number
US08269010B2

Reaction notes

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