2,4-Dimethoxybenzenesulfonyl chloride → N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)-2,4-dimethoxybenzenesulfonamide

HRID 2388064Notes

Reaction equation

HRID 2388064 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[N:10]=[CH:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2.[CH3:20][O:21][C:22]1[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:23]=1[S:30](Cl)(=[O:32])=[O:31]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:19][S:30]([C:23]2[CH:24]=[CH:25][C:26]([O:28][CH3:29])=[CH:27][C:22]=2[O:21][CH3:20])(=[O:32])=[O:31])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[N:10]=[CH:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2

Participants

3

Reactant 2

HCID 27346262,4-Dimethoxybenzenesulfonyl chlorideHCID 687937575-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine

Product 1

HCID 24852585N-(5-Chloro-6-(isoquinolin-3-yloxy)pyridin-3-yl)-2,4-dimethoxybenzenesulfonamide

Procedure

The title compound was prepared by reacting 5-chloro-6-(isoquinolin-3-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 2) and 2,4-dimethoxybenzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-6019eb1390fb46588bb57dd9747032a5
Source dataset
uspto-grants-2012_09
Patent number
US08269010B2

Reaction notes

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