4-Methoxybenzenesulfonyl chloride → N-(5-Chloro-6-(quinolin-3-yloxy)pyridin-3-yl)-4-methoxybenzenesulfonamide

HRID 2388067Notes

Reaction equation

HRID 2388067 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[CH:10]=[N:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2.[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([S:28](Cl)(=[O:30])=[O:29])=[CH:24][CH:23]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:19][S:28]([C:25]2[CH:24]=[CH:23][C:22]([O:21][CH3:20])=[CH:27][CH:26]=2)(=[O:30])=[O:29])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[CH:10]=[N:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2

Participants

3

Reactant 2

HCID 74014-Methoxybenzenesulfonyl chlorideHCID 687907985-Chloro-6-(quinolin-3-yloxy)pyridin-3-amine

Product 1

HCID 24852588N-(5-Chloro-6-(quinolin-3-yloxy)pyridin-3-yl)-4-methoxybenzenesulfonamide

Procedure

The title compound was prepared by reacting 5-chloro-6-(quinolin-3-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 1) and 4-methoxybenzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-a7ade023eadb4bf6af565922bda83532
Source dataset
uspto-grants-2012_09
Patent number
US08269010B2

Reaction notes

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