2,6-Difluorobenzenesulfonyl chloride → N-(5-Chloro-6-(quinolin-3-yloxy)pyridin-3-yl)-2,6-difluorobenzenesulfonamide

HRID 2388079Notes

Reaction equation

HRID 2388079 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[CH:10]=[N:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2.[F:20][C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([F:27])[C:22]=1[S:28](Cl)(=[O:30])=[O:29]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:19][S:28]([C:22]2[C:23]([F:27])=[CH:24][CH:25]=[CH:26][C:21]=2[F:20])(=[O:30])=[O:29])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[CH:10]=[N:11][C:12]2[C:17]([CH:18]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2

Participants

3

Reactant 2

HCID 27342712,6-Difluorobenzenesulfonyl chlorideHCID 687907985-Chloro-6-(quinolin-3-yloxy)pyridin-3-amine

Product 1

HCID 24852806N-(5-Chloro-6-(quinolin-3-yloxy)pyridin-3-yl)-2,6-difluorobenzenesulfonamide

Procedure

The title compound was prepared by reacting 5-chloro-6-(quinolin-3-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 1) and 2,6-difluorobenzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-5b1201150dcc43eeaab0cc754bf2b5fb
Source dataset
uspto-grants-2012_09
Patent number
US08269010B2

Reaction notes

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