Benzenesulfonyl chloride, 2,4-dichloro- → 2,4-Dichloro-N-(5-chloro-6-(quinolin-6-yloxy)pyridin-3-yl)benzenesulfonamide

HRID 2388087Notes

Reaction equation

HRID 2388087 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[CH:10]=[C:11]2[C:16](=[CH:17][CH:18]=1)[N:15]=[CH:14][CH:13]=[CH:12]2.[Cl:20][C:21]1[CH:26]=[C:25]([Cl:27])[CH:24]=[CH:23][C:22]=1[S:28](Cl)(=[O:30])=[O:29]>>[Cl:20][C:21]1[CH:26]=[C:25]([Cl:27])[CH:24]=[CH:23][C:22]=1[S:28]([NH:19][C:4]1[CH:5]=[N:6][C:7]([O:8][C:9]2[CH:10]=[C:11]3[C:16](=[CH:17][CH:18]=2)[N:15]=[CH:14][CH:13]=[CH:12]3)=[C:2]([Cl:1])[CH:3]=1)(=[O:30])=[O:29]

Participants

3

Reactant 2

HCID 204419Benzenesulfonyl chloride, 2,4-dichloro-HCID 688023605-Chloro-6-(quinolin-6-yloxy)pyridin-3-amine

Product 1

HCID 248529212,4-Dichloro-N-(5-chloro-6-(quinolin-6-yloxy)pyridin-3-yl)benzenesulfonamide

Procedure

The title compound was prepared by reacting 5-chloro-6-(quinolin-6-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 3) and 2,4-dichlorobenzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-43fbec1dbbcb43ddbe7a64723675d56e
Source dataset
uspto-grants-2012_09
Patent number
US08269010B2

Reaction notes

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