3,4-Dimethoxybenzenesulfonyl chloride → N-(5-Chloro-6-(quinolin-6-yloxy)pyridin-3-yl)-3,4-dimethoxybenzenesulfonamide

HRID 2388088Notes

Reaction equation

HRID 2388088 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:19])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[CH:10]=[C:11]2[C:16](=[CH:17][CH:18]=1)[N:15]=[CH:14][CH:13]=[CH:12]2.[CH3:20][O:21][C:22]1[CH:23]=[C:24]([S:30](Cl)(=[O:32])=[O:31])[CH:25]=[CH:26][C:27]=1[O:28][CH3:29]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:19][S:30]([C:24]2[CH:25]=[CH:26][C:27]([O:28][CH3:29])=[C:22]([O:21][CH3:20])[CH:23]=2)(=[O:32])=[O:31])[CH:5]=[N:6][C:7]=1[O:8][C:9]1[CH:10]=[C:11]2[C:16](=[CH:17][CH:18]=1)[N:15]=[CH:14][CH:13]=[CH:12]2

Participants

3

Reactant 2

HCID 27341833,4-Dimethoxybenzenesulfonyl chlorideHCID 688023605-Chloro-6-(quinolin-6-yloxy)pyridin-3-amine

Product 1

HCID 24853025N-(5-Chloro-6-(quinolin-6-yloxy)pyridin-3-yl)-3,4-dimethoxybenzenesulfonamide

Procedure

The title compound was prepared by reacting 5-chloro-6-(quinolin-6-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 3) and 3,4-dimethoxybenzene-1-sulfonyl chloride.

Sources & evidence

ORD record
ord-a9eef85f7b3d45efba523b4eddd833ee
Source dataset
uspto-grants-2012_09
Patent number
US08269010B2

Reaction notes

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