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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2388089Generated: October 27, 2026

2,4-Difluorobenzenesulfonyl Chloride → N-(5-Chloro-6-(quinolin-6-yloxy)pyridin-3-yl)-2,4-difluorobenzenesulfonamide

https://huagongshe.com/reaction/2388089

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorobenzenesulfonyl ChlorideHCID 2734273—
Reactant5-Chloro-6-(quinolin-6-yloxy)pyridin-3-amineHCID 68802360—
ProductN-(5-Chloro-6-(quinolin-6-yloxy)pyridin-3-yl)-2,4-difluorobenzenesulfonamideHCID 24853026—

Reaction Steps

The title compound was prepared by reacting 5-chloro-6-(quinolin-6-yloxy)pyridin-3-amine (obtained as per procedure described in preparation 3) and 2,4-difluorobenzene-1-sulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08269010B2
Source datasetuspto-grants-2012_09
ORD IDord-573785339017408680a173036000fbcc
Source noteuspto-grants-2012_09