Benzoyl Peroxide → HCID 67530139, compound

Participants

Reaction Steps

Ethyl 3-(furan-2-yl)-4-methylisoxazole-5-carboxylate (5.8 g, 26.2 mmol), NBS (5.6 g, 31.5 mmol), and benzoyl peroxide (0.64 g, 2.62 mmol) were added to 150 mL of carbon tetrachloride and the mixture was refluxed for 16 h. Reaction mixture was filtered and concentrated. The residue was purified by flash chromatography (0-30% EtOAc/hexanes) to give 1.7 g of the title compound. MS: (+) m/z 300.31, 322.28 (M+1, 79Br/81Br).

Provenance & Evidence