HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-5-iodopyridine → 1-[2-(Tert-butyl-dimethyl-silanyloxy)-ethyl]-5-iodo-1h-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-5-iodopyridine | HCID 459500 | — |
| Reactant | (2-Bromoethoxy)-tert-butyldimethylsilane | HCID 3608067 | — |
| Product | 1-[2-(Tert-butyl-dimethyl-silanyloxy)-ethyl]-5-iodo-1h-pyridin-2-one | HCID 59541876 | — |
Reaction Steps
The title compounds were prepared as white solids from the alkylation of 5-iodo-1H-pyridin-2-one with BrCH2CH2OTBS (Aldrich) using the procedure described in Step A of Example 38.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08269015B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-d306150ea5e04358981d6b7144b69b65 |
| Source note | uspto-grants-2012_09 |