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HRID2389147

反应详情

EQUATION

反应方程式

HRID 2389147 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1cncnc1
HCID2795193

5-Pyrimidinylboronic acid

C4H5BN2O2

结构：CC(C)(C)[C@H]1CC[C@H](Oc2ccc3cc([C@]4(C)COC(=O)N4)ccc3c2-c2ccc(OC(F)(F)F)cc2)CC1
HCID178445727

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)[C@H]1CC[C@H](Oc2ccc3cc([C@]4(C)COC(=O)N4)ccc3c2-c2cncnc2)CC1
HCID178445729

未命名化合物

收率 85%

PROCEDURE

实验过程

(R)-4-(6-(trans-4-tert-butylcyclohexyloxy)-5-(pyrimidin-5-yl)naphthalen-2-yl)-4-methyloxazolidin-2-one was synthesized as per (R)-4-(6-(trans-4-tert-butylcyclohexyloxy)-5-(4-(trifluoromethoxy)phenyl)naphthalen-2-yl)-4-methyloxazolidin-2-one (Example 220) in 85% yield using pyrimidin-5-ylboronic acid (0.0885 g, 0.000714 mol) as the reagent.