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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2389188Generated: November 1, 2026

HCID 178447444, compound → HCID 178500166, compound

https://huagongshe.com/reaction/2389188

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178447444HCID 178447444—
ReactantHCID 178500167HCID 178500167—
ProductHCID 178500166HCID 17850016651%

Reaction Steps

4-[5-Iodo-6-(cis-4-trifluoromethyl-cyclohexyloxy)-naphthalen-2-yl]-4-nitro-pentanoic acid methyl ester was synthesized as per 4-[5-iodo-6-(trans-4-trifluoromethyl-cyclohexyloxy)-naphthalen-2-yl]-4-nitro-pentanoic acid methyl ester (Example 281) in 51% yield, using 4-nitro-4-[6-(cis-4-trifluoromethyl-cyclohexyloxy)-naphthalen-2-yl]-pentanoic acid as the starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08269043B2
Source datasetuspto-grants-2012_09
ORD IDord-c88843ca7a4247baa79dd037f1804a27
Source noteuspto-grants-2012_09