Formic Acid → HCID 59408364, compound

Participants

Reaction Steps

190.5 g (0.55 mol) of 8-[4-(4-propylphenyl)cyclohexyl]-1,4-dioxaspiro[4.5]-decane are stirred vigorously for 19 h together with 480 ml of formic acid in 900 ml of toluene. Water is added, and the organic phase is separated off. The aqueous phase is extracted with MTBE, and the combined organic phases are washed successively with water, sat. sodium hydrogencarbonate solution and sat. sodium chloride solution. The solution is dried using sodium sulfate and concentrated to completion. The crude product is recrystallised from n-heptane.

Provenance & Evidence