Bromine → N-(3-(2-bromoacetyl)-4-chlorophenyl)-3,5-dimethoxybenzamide

HRID 2389255Notes

Reaction equation

HRID 2389255 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([NH:11][C:12](=[O:23])[C:13]2[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([O:21][CH3:22])[CH:14]=2)[CH:7]=[CH:8][C:9]=1[Cl:10])(=[O:3])[CH3:2].[Br:24]Br>>[Br:24][CH2:2][C:1]([C:4]1[CH:5]=[C:6]([NH:11][C:12](=[O:23])[C:13]2[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([O:21][CH3:22])[CH:14]=2)[CH:7]=[CH:8][C:9]=1[Cl:10])=[O:3]

Participants

3

Reactant 2

HCID 24408BromineHCID 69236157N-(3-acetyl-4-chlorophenyl)-3,5-dimethoxybenzamide

Product 1

HCID 86623924N-(3-(2-bromoacetyl)-4-chlorophenyl)-3,5-dimethoxybenzamide

Procedure

Procedure C was performed using N-(3-acetyl-4-chlorophenyl)-3,5-dimethoxybenzamide (0.1 g, 0.3 mmol) and Br2 (0.017 ml, 0.33 mmol to afford N-(3-(2-bromoacetyl)-4-chlorophenyl)-3,5-dimethoxybenzamide.

Sources & evidence

ORD record
ord-7988ce7449174d65bfe2fde58a498d8b
Source dataset
uspto-grants-2012_09
Patent number
US08273743B2

Reaction notes

Loading…