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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 238933Generated: October 29, 2026

Ethylamine → N-[4-(1-Aminoethyl)-2-fluorophenyl]methanesulfonamide

https://huagongshe.com/reaction/238933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
ReactantN-[2-Fluoro-4-(N-hydroxyethanimidoyl)phenyl]methanesulfonamideHCID 71418418—
ProductN-[4-(1-Aminoethyl)-2-fluorophenyl]methanesulfonamideHCID 21097518—

Reaction Steps

Through similar procedure to that in Example 97-3 excepting using 3′-fluoro-4′-(methylsulfonylamino)acetophenone oxime (13-9) as a starting material, 3′-Fluoro-4-(methylsulfonylamino)phenyl]ethyl amine (13-12, MK-232) having following physicochemical properties was synthesized:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642657B2
Source datasetuspto-grants-2014_02
ORD IDord-ddeb4398d3034bb3b7a15adfe9e04b77
Source noteuspto-grants-2014_02