HRID23895

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1672

3-Methoxypropylamine

C4H11NO

结构：COCCCn1c(-c2ccc(C(C)(C)C)cc2)nc2ccc(OCCCCCC(=O)OC)cc21

HCID10226886

未命名化合物

PRODUCTS

生成物

结构：COCCCNC(=O)CCCCCOc1ccc2nc(-c3ccc(C(C)(C)C)cc3)n(CCCOC)c2c1

HCID10142914

未命名化合物

PROCEDURE

实验过程

2-(4-tert-Butyl-phenyl)-6-[(5-(methoxycarbonyl)pentyl)oxy]-1-(3-methoxy-propyl)-benzimidazole is reacted with 3-methoxypropylamine according to general operating instructions 7. 2-(4-tert-Butyl-phenyl)-1-(3-methoxy-propyl)-6-[(5-((3-methoxy-propyl)amino-carbonyl)-pentyl)oxy]-benzimidazole is obtained as a yellow solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-25c4ec6eeff645969075f65bd48d134b
来源数据集: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06855714B2
来源说明: uspto-grants-2005_02

反应 SMILES

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[N:15]([CH2:16][CH2:17][CH2:18][O:19][CH3:20])[C:14]3[CH:21]=[C:22]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][C:31](OC)=[O:32])[CH:23]=[CH:24][C:13]=3[N:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:35][O:36][CH2:37][CH2:38][CH2:39][NH2:40]>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[N:15]([CH2:16][CH2:17][CH2:18][O:19][CH3:20])[C:14]3[CH:21]=[C:22]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][C:31]([NH:40][CH2:39][CH2:38][CH2:37][O:36][CH3:35])=[O:32])[CH:23]=[CH:24][C:13]=3[N:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]