HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Chlorobenzo(b)thiophene-2-carbonyl chloride → tert-Butyl {4-[(4'-acetyl-4-methoxy-biphenyl-3-ylmethyl)-(3-chloro-benzo[b]thiophene-2-carbonyl)-amino]-cyclohexyl}-methyl-carbamate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Chlorobenzo(b)thiophene-2-carbonyl chloride | HCID 519898 | — |
| Edukt | tert-Butyl {4-[(4'-acetyl-4-methoxy-biphenyl-3-ylmethyl)-amino]-cyclohexyl}-methyl-carbamate | HCID 59683576 | — |
| Produkt | tert-Butyl {4-[(4'-acetyl-4-methoxy-biphenyl-3-ylmethyl)-(3-chloro-benzo[b]thiophene-2-carbonyl)-amino]-cyclohexyl}-methyl-carbamate | HCID 59683629 | — |
Reaktionsschritte
Biaryl amine 19 (400 mg, 0.86 mmol) is treated with 3-chloro-benzo[b]thiophene-2-carbonyl chloride (237 mg, 1.03 mmol) using Method D to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08273747B2 |
| Quelldatensatz | uspto-grants-2012_09 |
| ORD ID | ord-55e7953c68714d1a9ef10054913b6131 |
| Quellennotiz | uspto-grants-2012_09 |