N-(4-Bromophenyl)-N-methyl-formamide → tert-Butyl (4-{[4'-(formyl-methyl-amino)-4-methoxy-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamate

Participants

Role	Name	HCID	Charge
Reactant	N-(4-Bromophenyl)-N-methyl-formamide	HCID 15004464	—
Reactant	3-{[4-(BOC-methyl-amino)-cyclohexylamino]-methyl}-4-methoxy-benzene boronic acid	HCID 25208191	—
Product	tert-Butyl (4-{[4'-(formyl-methyl-amino)-4-methoxy-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamate	HCID 25208192	—

Boronic acid 4 (260 mg, 0.66 mmol) is coupled to aryl bromide 51 (170 mg, 0.79 mmol) using Method B to give the title compound.