5-Bromopyrimidine → 3-Chloro-benzo[b]thiophene-2-carboxylic acid (2-methoxy-5-pyrimidin-5-yl-benzyl)-(4-methylamino-cyclohexyl)-amide dihydrochloride

Participants

Role	Name	HCID	Charge
Reactant	5-Bromopyrimidine	HCID 78344	—
Reactant	3-{[[4-(BOC-methyl-amino)-cyclohexyl]-(3-chlorobenzo[b]thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-benzene boronic acid	HCID 59683646	—
Product	3-Chloro-benzo[b]thiophene-2-carboxylic acid (2-methoxy-5-pyrimidin-5-yl-benzyl)-(4-methylamino-cyclohexyl)-amide dihydrochloride	HCID 86618969	—

The title compound is prepared from boronic acid 5 (25 mg, 43 μmol) and 5-bromopyrimidine (5.6 mg, 36 μmol) in accordance with Method L2.