HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-methylpyridine → tert-Butyl {4-[2-ethoxy-5-(6-methyl-pyridin-3-yl)-benzylamino]-cyclohexyl}-methyl-carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-methylpyridine | HCID 1201020 | — |
| Reactant | HCID 59683589 | HCID 59683589 | — |
| Product | tert-Butyl {4-[2-ethoxy-5-(6-methyl-pyridin-3-yl)-benzylamino]-cyclohexyl}-methyl-carbamate | HCID 59683542 | — |
Reaction Steps
Boronic acid 11 (812 mg, 2.0 mmol) is coupled to 5-bromo-2-methylpyridine (344 mg, 2.0 mmol) using Method A to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273747B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-28e46a37fe9b4529bf09b2787fda0d4b |
| Source note | uspto-grants-2012_09 |