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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2389651Generated: October 26, 2026

3-Bromopyridine → tert-Butyl [4-(2-methoxy-5-pyridin-3-yl-benzylamino)-cyclohexyl]-methyl-carbamate

https://huagongshe.com/reaction/2389651

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
Reactant3-{[4-(BOC-methyl-amino)-cyclohexylamino]-methyl}-4-methoxy-benzene boronic acidHCID 25208191—
Producttert-Butyl [4-(2-methoxy-5-pyridin-3-yl-benzylamino)-cyclohexyl]-methyl-carbamateHCID 59683605—

Reaction Steps

Boronic acid 4 (500 mg, 1.27 mmol) is coupled to 3-bromopyridine (202 mg, 1.27 mmol) using Method A to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273747B2
Source datasetuspto-grants-2012_09
ORD IDord-8f9545d981b84eb39164fbd8e47d09c7
Source noteuspto-grants-2012_09